| The Life Extension Foundation Forums > LEF Public Forums > Dietary Supplements > HOW TO REVERSE GREY HAIR? | Forum Quick Jump
|
|  Bhavani Registered Member
       Date Joined Jun 2006 Total Posts : 14 | Posted 6/12/2006 9:17 AM (GMT -5) |   | Reverse, Where did you purchase your root from and what application of it did you use? | | Back to Top | | |
 |  flowergirl Registered Member
       Date Joined May 2006 Total Posts : 54 | Posted 6/12/2006 1:02 PM (GMT -5) |   | | have taken goji berries on and off for a while, never noticed any effect on my hair. i only take a handful a day so that may be why, or maybe it just had no effect! | | Back to Top | | |
   |  zorba990 Registered Member
       Date Joined Jul 2004 Total Posts : 710 | Posted 6/12/2006 4:16 PM (GMT -5) |   |
flowergirl said...
zorba990 said... I think you need more information on why Bimatoprost causes this effect. Bimatoprost is a synthetic prostaglandin. So this immediately makes me ask the question what natural prostaglandin is it possibly substituting for in its effect in treating glaucoma, and does the upregulation of that natural prostaglandin also effect pigmentation?
Now I am making an assumption here, and it may be that there is no natural prostaglandin that will effect pigmentation. But, in my experience, nearly every pharmaceutical has a more natural, safer, alternative that works nearly as well without the associated side effects that pharmaceuticals seem to always have.
Also, some prostaglandins have inflammatory effects e.g. E2 so the pathways need some clarification.
Can anyone draw a pathway from a prostaglandin to melanin synthesis, release, etc? how can we find out which natural prostaglandin its derived from? always prefer the natural alternative!
Bimatoprost is a derivative of the prostamide F 2α, which is enzymatically formed from PGF 2α and should act similar like PGF 2α, but has a lower receptor affinity.
| | Back to Top | | |
 |  Bhavani Registered Member
       Date Joined Jun 2006 Total Posts : 14 | Posted 6/13/2006 9:59 AM (GMT -5) |   | Reverse,
Where in Florida was the Asian store? I'm in FL too. | | Back to Top | | |
 |  PASSABOX Registered Member
       Date Joined Feb 2006 Total Posts : 24 | Posted 6/13/2006 9:59 AM (GMT -5) |   | | | |
 |  zorba990 Registered Member
       Date Joined Jul 2004 Total Posts : 710 | Posted 6/13/2006 10:00 AM (GMT -5) |   | Here is a better explanation:
http://tinyurl.com/oek4x
"We now show that PGF2alpha stimulates the activity and expression of tyrosinase, the rate-limiting enzyme in melanin synthesis."
Of course, this doesn't necessarily mean that prostaglandins have anything to do with hair color, but it may be that they will stimulate some due to the increase in melanin synthesis.
But this is a stimulatory effect. So its possibly not the answer for the long term, since it may just wear out the melanocytes faster, or use up the tyrosine, copper, PABA, pantothenate, etc, if you are not supplementing with plenty of nutrients.
What is really needed is intervention at the point in the process where stem cells create new melanocytes to replace the old, oxidized, dying ones, not overstimulation of the ones that are almost at the end of their lifecycle. | | Back to Top | | |
 |  flowergirl Registered Member
       Date Joined May 2006 Total Posts : 54 | Posted 6/13/2006 10:00 AM (GMT -5) |   | | Bimatoprost is a derivative of the prostamide F2, which is enzymatically formed from PGF2 and should act similar like PGF2 but has a lower receptor affinity. | | Back to Top | | |
 |  Slider Registered Member
       Date Joined May 2006 Total Posts : 18 | Posted 6/13/2006 12:34 PM (GMT -5) |   | | | |
  |  reverse Registered Member
       Date Joined May 2006 Total Posts : 64 | Posted 6/14/2006 11:01 AM (GMT -5) |   | Slider, great link. Reading that keeps me optomistic. The competition must be fierce on finding a remedy to reverse gray hair. I read somewhere hair color is a $7 billion-a-year industry so whomever finds and patents a safe, effective cure will be a rich, rich person/company. So with that kind of financial reward, I imagine more money being poured into research. I do hope it happens in the near future :)
Bhavani: Which coast do you live on in FL?
Everyone: Still doing the Bao Saka experiment and will probably give up at the 2 1/2 month marker. It's been a little over 5 weeks and nothing :( | | Back to Top | | |
 |  flowergirl Registered Member
       Date Joined May 2006 Total Posts : 54 | Posted 6/14/2006 11:02 AM (GMT -5) |   | ok, so firstly, why do you think stimulating the hair follicle to reproduce melanin would make it "run out" ? surely the other hair follicles that keep their color manage to exist for years without this happening?
and as for the nesta research in bradford from sliders message, again, they mention a "natural chemical". reckon they're talking about the same thing?
it seems like there is a race out there to patent the discovery real fast, which is great, and feels imminent. but would be great to find out what the natural derivatives are. | | Back to Top | | |
 |  Bhavani Registered Member
       Date Joined Jun 2006 Total Posts : 14 | Posted 6/15/2006 9:32 AM (GMT -5) |   | reverse,
I live on the east coast in South Florida. I haven't tried any local markets as yet. I did buy several plants from a ginger plant grower here in Florida. They are called "Kaempferia Parviflora" which where propagated from an original plant from Thailand and is to my understanding the Krachai or black ginger. They are small though and will take some time to grow before I will be able to harvest them. So I am going to start looking here locally to see if I can find the fresh root. | | Back to Top | | |
 |  Slider Registered Member
       Date Joined May 2006 Total Posts : 18 | Posted 6/15/2006 9:32 AM (GMT -5) |   | | | |
 |  zorba990 Registered Member
       Date Joined Jul 2004 Total Posts : 710 | Posted 6/15/2006 9:32 AM (GMT -5) |   |
flowergirl said... ok, so firstly, why do you think stimulating the hair follicle to reproduce melanin would make it "run out" ? surely the other hair follicles that keep their color manage to exist for years without this happening?
and as for the nesta research in bradford from sliders message, again, they mention a "natural chemical". reckon they're talking about the same thing?
it seems like there is a race out there to patent the discovery real fast, which is great, and feels imminent. but would be great to find out what the natural derivatives are. The primary reason for gray hair is that the worn out melanocyte, which is
supposed to be replaced by a new cell via the stem cells, is not replaced.
(Presumably due to lack of enough healthy living stem cells) No melanocyte = no melanin. So the fact is that the cells do get worn out, and die just like evey other cell in the body.
The process of producing melanin is an oxidative one. So antioxidants can certainly help delay the aging of the cell. And, of course, supplying enough raw materials for the melanin forming reaction can help the cell's melanin production be more efficient. But simply stimulating the melanocytes to produce more melanin, does not keep the cells young and healthy. In fact, it likely does the opposite.
So say, for instance, that ingesting or topically applying a tyrosine compound
stimulates increased melanin synthesis. More synthesis = more oxidation = more
wearing out of the cells. So while you may see a hair getting darker in the short term, you are sending the melanocyte to a quicker death via upregulation of an oxidative pathway.
If you simultaneously increase antioxidants (orally, topically, whatever), and protect the cells from UV radiation (sunscreen in the shampoo, PABA, etc) and other toxins, you might come out equal. But eventually oxidation will win and the melanocyte will die.
So the key is get the body to produce more of the STEM CELLS. Then the dying melanocytes can always be replaced. Couple that with the proper nutrition needed to supply the raw materials for synthesis, and your hair would stay non-gray forever.
When you are young you have plenty of stem cells alive to supply new
melanocytes. Perhaps someday you will have your own stem cells extracted, multiplied, and injected back into you as a re-youthing method.
Or some wise person will figure out the set of circumstances that causes the body to produce these stem cells and duplicate it to stimulate the body to produce them on demand.
Until then I doubt any chemical, herb, vitamin, etc will have more than a delaying effect on gray hair. This delaying effect may be enough to appear as a full reversal, since hair grows in cycles, and is likely fed by multiple sets of melanocytes. The difference being that a real full reversal would restore the system to the state where the hair would continue to appear as normal color well after treatment with any nutrients, etc was stopped.
| | Back to Top | | |
 |  flowergirl Registered Member
       Date Joined May 2006 Total Posts : 54 | Posted 6/16/2006 12:05 PM (GMT -5) |   | thanx zorba, thats a clear answer. all i can say is bring on the day when some genius figures out a safe easy way to reproduce/reactivate the stem cells!
until then keep feeding on antioxidants?! | | Back to Top | | |
 |  TheNutster Registered Member
       Date Joined Jun 2006 Total Posts : 6 | Posted 6/18/2006 12:26 PM (GMT -5) |   | | Try supplementing with 500 mg. PABA (para aminobenzoic acid) for awhile until you see a change back in color. I use it only when I need it. I'm 69. I use Solgar. | | Back to Top | | |
  |  peakbagger Registered Member
       Date Joined Sep 2005 Total Posts : 69 | Posted 6/18/2006 12:27 PM (GMT -5) |   | Just in case someone actually tried brewing this drink, I amend the soy milk and yogurt to 1/2 cup and 1 cup respectively. I prefer the Stonyfield Farm yogurt for it's superior active culture variation & counts. You can take all the vitamins and good foods you want, but if your digestive system is impaired, it won't matter much.
My hair, which at age 51, has at most only a handful of grey hairs, darkened significantly when I changed my diet about 6-7 years ago. I have no idea what ingredients did it but it went from a sandy brown to a dark brown and seemed to thicken. Per the lady that cuts my hair, it darkened 3-4 shades. At first she thought I was dying my hair but I pointed out a couple of the greys that are on the side to disprove that theory. The lady that cuts my hair suggested it may be the minerals in the ingredients -- seems reasonable and along with the healthier colon from the yogurt, perhaps I am digesting more efficiently. I certainly have zero elimination problems.
The big change in diet was taking anti-oxidants (not LEF at that time) and this power drink I have every morning: 1/4 cup organic soymilk 1/2 cup organic yogurt with multiple active cultures banana frozen blueberries 3/4 cup or so teaspoon or more of organic apple vinegar 2 scoops whey flavored whey powder -- no nasty artificial sweeteners Super Green Max Herbal Mix from Swanson's Vitamins (approx tablespoon) near tablespoon of Earthrise Organic Spirulina 1 1/2 tablespoon Organic flaxseed oil 1 1/2 tablespoon lecithin soy granules
This stuff holds me over from 6-7 am to 10-11 o'clock easily -- start out with smaller portions, this is very nutrient-dense -- my body did not adapt immediately. The drink, which is like a shake in consistency, is also very helpful for gulping down vitamins.Post Edited (peakbagger) : 6/29/2006 1:53:58 PM (GMT-4) | | Back to Top | | |
 |  PASSABOX Registered Member
       Date Joined Feb 2006 Total Posts : 24 | Posted 6/20/2006 1:00 PM (GMT -5) |   | Reverse and Bhavani:
I´m waiting your searchs on the black ginger roots or plants in Florida. I live in Sao Paulo/Brazil and have friends in Orlando and Miami, so if you guys find anyplace to buy it pls keep me posted.
Good luck. | | Back to Top | | |
 |  BartSimpson Registered Member
       Date Joined Apr 2006 Total Posts : 56 | Posted 6/20/2006 1:01 PM (GMT -5) |   | Did we all give up already?
I'm trying a composite of vitamins/PABA (100 mg daily). I'm half month already.
I will give a full update every month. | | Back to Top | | |
 |  BartSimpson Registered Member
       Date Joined Apr 2006 Total Posts : 56 | Posted 6/21/2006 10:14 AM (GMT -5) |   | AssuieDavid did you get anymore hair restored?
If you did, i'm going to copy your regimen. | | Back to Top | | |
 |  reverse Registered Member
       Date Joined May 2006 Total Posts : 64 | Posted 6/21/2006 10:17 AM (GMT -5) |   | | I only found the white and after 6 weeks, it hasn't worked. | | Back to Top | | |
 |  reverse Registered Member
       Date Joined May 2006 Total Posts : 64 | Posted 6/23/2006 3:25 PM (GMT -5) |   | | So, did PABA actually reverse gray hair or just delay the onset of it? | | Back to Top | | |
 | 1234 posts in this thread. Viewing Page : | | Forum Information | Currently it is Sunday, November 22, 2009 5:49 PM (GMT -5) There are a total of 36,077 posts in 7,374 threads. In the last 3 days there were 5 new threads and 23 reply posts. View Active Threads
| | Who's Online | This forum has 8801 registered members. Please welcome our newest member, Prelude. 1 Guest(s), 0 Registered Member(s) are currently online. Details
|
Forum powered by dotNetBB v2.42EC SP3 dotNetBB © 2000-2009 All Contents Copyright © 2004, Life Extension™. All rights reserved. |
|
|