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Niko
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   Posted 1/29/2007 11:08 AM (GMT -5)    Quote This PostAlert An Admin About This Post.

L’Oreal, the French cosmetic giant, (who brought you the L-Taurine patent as a treatment for MPB ) has developed a drug called “Promel” that reportedly returns gray hair back to its natural color within 2-4 months.  It is apparently based upon addressing 2 genes that are related to the malfunctioning of the melanocytes.  

Rumor has it that it will be available within 3 months in Europe, no word yet on the costs.

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dang
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   Posted 1/29/2007 11:30 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
zorba - do you think copper peptides (ie. folligen) would have the same effect as ionic copper?
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zorba990
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   Posted 1/29/2007 3:24 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
dang said...
zorba - do you think copper peptides (ie. folligen) would have the same effect as ionic copper?
It has been reported to have the same effect.  It might be worth a try - seems relatively inexensive and many people do use it for calming down scalp inflammation caused by minox.  It seems fairly highly concentrated, though and I would wonder about long term copper overload in using it with a penetrating lotion.
 
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reverse
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   Posted 1/31/2007 12:18 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Ok, so where's all this information coming from regarding L'Oreal's "promeal"? I tried to get information months ago and couldn't get any. Does anyone have any reliable sources?  Available in Europe in 3 months?  Please tell me/us where you heard this.
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dLaertios
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   Posted 1/31/2007 5:15 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
It is possible that topical application of ionic or other form of copper to have a dye effect.
I was sceptical after I found this http://www.freepatentsonline.com/4173453.html .

"The copper sulfide generated within the hair follicles provides a more or less permanent coloration. More particularly, in the hair, free sulfur is slowly changed to hydrogen sulfide by the action of microorganisms in the scalp ...".

The meaning is that if we add a little quantity of sulfur instead of Paba to ionic copper and apply this topically to our scalp we will have a dye effect and our hair will start to color. Am I right?

Maybe the ionic copper alone reacts with other microorganisms and we have the copper sulfide or something else which dyes the roots of hairs gradually.

I also started to use topical colloidal copper and Paba to scalp for a week -daily and I think that this remedy works too but it 's too early to tell anything. I am curious if another one started to see differences to hair color after only one week of topical application of copper and Dmae-H3 or Paba or it is just a mind game.

Give a try to topical solutions maybe copper + sulfur do the trick although it will be just a dye effect.
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teenagegraygal
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   Posted 2/1/2007 12:40 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
It is easy to know whether the solution is giving dying effect or working internally. If the existing gray hair remains gray and if the root of the gray strand gradually turns to dark then it means the solution is working internally.
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dLaertios
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   Posted 2/1/2007 3:32 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Teenagegraygal,
I don't think that it is so easy to know. The patent says that microorganisms inside the hair follicle make the whole procedure of dying.
Also I have read that Paba and sulfur are antagonistic. For the last week I apply topical colloidal copper + Paba every day. As I check thoroughly my side hair I definitely have less gray hair since I started to reverse them (9 months ago). Maybe the topical application of copper boosted my regimen reversal.
Right now I am curious what will happen after two or three months following my regimen.
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teenagegraygal
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   Posted 2/2/2007 11:34 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
Does anyone know the cause of convulsions? I have seen few people who get convulsions but to my surprise i noticed all of them have also got gray hair in their childhood. I don't think the vice versa is true as there are so many people (like me) who are suffering from this gray hair in their early teens though they have never got convulsions before. I always wondered that convulsions and gray hair has got very close relationship. I just wanted to put it across to u all as i thought it may give a clue in finding out the right medicine for gray hair.
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Vincentvangogo
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   Posted 2/2/2007 3:42 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Teenagegreygal, I've not seen any connection with convulsions, but I read somewhere on the net that someone had noticed a connection between schizophrenia and premature greying (I've also seen this in a couple of people with the illness.) The theory was that schizophrenics might not be able to metabolize a certain vitamin (B2?) and that this led to another chemical being produced in their bodies that was close in structure to a hallucinogenic drug. I think the molecular structure of LSD is sometimes used to understand schizophrenia (the gene??) and there certainly seem to be a lot of similarities been schizophrenic episodes and people who are tripping/hallucinating, hence I thought there might be something in this theory.
 
 Another interesting thing was that they mentioned some schizophrenics improved by simply giving them mollasses every day, which I think contains this B vitamin and I  know that some people claim molasses has restored their hair to its original colour. 
As you must have guessed already I am not a scientist, but perhaps someone out there can make something of all this. 
 
- Could one of the drugs used to treat seizure disorders cause graying? - mod
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brm
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   Posted 2/2/2007 9:51 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Hi dLaertios.You seem to be case n°2 of reversal after Zorba. Here are some questions for you.

1°) Would you please tll us what your exact regimen has been over the past nine months to obtain the reversal effect?

2°) You are currently using colloidal copper + PABA. Where do you get these ingredients from?

Thank you.
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dLaertios
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   Posted 2/3/2007 1:30 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Hi, my results aren't as dramatic as Zorba's.

But my reversal is more than 10% for sure. Become more noticable after I started to apply the topical solution of colloidal copper and Paba.

1) My daily regimen now is
a) Blackstrap mollasses+acv+honey and 15 mg beta carotene in the morning
b) B+C supplement after lunch (1000 mg C, 50mg of each B5, PABA, Folacin, B12 and other of B complex)
c) E 1000 iu after dinner.
2)
I apply castor oil daily
and I make the colloidal (if you search the net you can find instruction how to make or to buy a device) with regular water after I have drop the content of a Paba 550 mg tablet in there.

If I had to chooce between one supplement and one topical I would go for the
super B+C and colloidal copper with Paba.
Good luck (I need it too).
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StarGazer
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   Posted 2/4/2007 8:01 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Promel is a proven Internet hoax. L'Oreal is working anti-greying research and has been for some time, but they are not developing a drug called Promel, and they are not close to any such product that will be commercialized.

Any other reports are bull s___.

Someone made up a hoax about Promel, then submitted it to news feeds, and it was picked up by some websites in order to gain additional traffic.

I'm not sure if it was this board or another board that posted responses from L'Oreal of France in which the reps said that there is no real proposed pill called Promel or any other such pill.

If L'Oreal did ever come out with such a product, it would probably be a lotion or something added to the shampoo, and not a pill.

A pill would require clinical trials in all likelihood, which would mean many many years down the road for approval - even if there was such a pill in development.
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StarGazer
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   Posted 2/4/2007 8:02 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Thank you for visiting L'Oréal Paris on the Web.

Recently, L'Oréal's scientists presented significant new research about what makes hair grow curly or straight, and about why hair turns gray. It is possible that, at some point in the future, these discoveries may lead to a pill that controls hair shape or color. However, such a pill is not available at this time.

We hope this information is helpful.

Sincerely,
Cynthia Bosse
Consumer Affairs Advisor
Ref # 3529851

Now let's put the Promel b.s. to rest once and for all. There is no such drug about to be available.
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flowergirl
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   Posted 2/10/2007 1:34 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
aussiedavid have you been able to get a formula from your chemist yet?? and have you had any results? i see thru this post you had a few hairs reverse. has there been any greater reversal than that yet?

and zorba, you say that you think the dmae-h3 and the copper were the key ingredients, but to achieve a reversal, do you think you should add to that ?? you mention melatonin and vit d and sodzyme/glisodin. i'm not much of a chemist, so i'm trying with the dmae-h3 and ionic copper, but i wanna make sure im not wasting time if i need other ingredients to facilitate the efficacy of the dmae-h3 and ionic copper.

i know you've posted these things before, but as you say, your research and formula is ongoing, so i'd like to know where you're at with it, if you wanna share!

thanx to everyone for sharing all their info!!
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StinkyJoe
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   Posted 2/10/2007 5:05 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Hey Zorba!
 
Thanks for all the info you've provided. You have not mentioned the dermaroller in a while.
 
Are you still using it? How useful is it? Which one did you get?
 
The Dermarollers appear to have a wide range of prices (is it a trademarked name?), so it is hard to know which one to get.
 
Thanks,
StinkyJoe
yeah
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zorba990
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   Posted 2/10/2007 7:03 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
No, not really (dermaroller). The main problem with it is it bends the hair shafts no matter how careful I was). This makes it dificult to style thick hair.  I also have doubts about long term puncturing of the skin causing scarring even though
the creators say this won't happen due to the small size of the needles being used.

I think most topical forumulas can go right down the hair shaft no problem. If you look at recent evidence on stem cell stimulation by vitamin d, I'd say this is a good bet to add (I'm puting in enough for 1200 IU for each topical dose). I didn't notice anything from carnosine so I'm betting N-Acetyl-carnosine would work better (its horrendously expensive though).  Didn't notice anything from histidine but for sulfur intolerance people it might be crucial since 6 histidines are needed during melanin production and histidine is low in most cooked diets.

Sonic blending with phosphatidylserine might be an interesting next step... (looking for bulk liquid supplier now) as opposed to the usual PC used in liposomes. I think PS has special role in stem cell production but no definitive proof yet.

Post Edited (zorba990) : 2/10/2007 6:47:36 PM (GMT-5)

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JRL
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   Posted 2/11/2007 3:16 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Zorba,

I'm a new member, and after reading through the old posts I have been impressed by your knowledge and results and believe I want to try out your topical application for myself. The most recent post citing your recipe states that it is:

1 dropper DMAE-H3
1 capful ionic copper
1T arginine
1T carnosine

You also mention is a past posts that you apply your topical "straight" and that you just mix it up "on the fly."

My questions:

- Are the arginine and carnosine in powder form? And if not where can I find liquid forms?

- How do you mix up the ingredients? If I understand "straight" as not using any sort of medium for the mixing of ingredients you would end up with a very small amount of product for application to a whole head of hair.

- In this post you seem to infer that carnosine is not showing results, so I guess you are dropping that from you topical?

Sorry I'm so ignorant, but it's better to ask and look dumb once than to be dumb all of your life.

Post Edited (JRL) : 2/11/2007 6:23:27 PM (GMT-5)

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flowergirl
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   Posted 2/11/2007 3:16 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
zorba, how often are you applying your formula? and do u put it on at nite?? are u stil using melatonin? and the vit d ur adding, what form are you using?? do u add it to a liquid, or just use the ionic copper as the liquid base?

& do you think msm is a no-no??
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Redneck Rivera
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   Posted 2/11/2007 3:17 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Guys, check these out:
 
 
 
 
 
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AussieDavid
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   Posted 2/11/2007 3:24 PM (GMT -5)    Quote This PostAlert An Admin About This Post.

Hi flowergirl,

No formula as yet. Apparently getting everything I want into a stable solution is near impossible. Will post here when I have any more information.

I had found a few hairs last year that had dark roots and grey tips. They must have just been 'one off's' since I don't think I have noticeable results with the supplement regime I have been following. All kinda disappointing really. I'm hoping the topical solution will make a difference.

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zorba990
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   Posted 2/11/2007 8:03 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
flowergirl said...
zorba, how often are you applying your formula? and do u put it on at nite?? are u stil using melatonin? and the vit d ur adding, what form are you using?? do u add it to a liquid, or just use the ionic copper as the liquid base?

& do you think msm is a no-no??
Applying most every day.  Didn't notice anything positive from MSM in the topical formula and based on previous experience I would avoid it for gray hair but might use it for thinning without graying.
 
 
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dang
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   Posted 2/11/2007 8:05 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
"Guys, check these out:

Milanitin : http://www.milanitin.com/index.htm


MELATAB : http://melatab.com/index.html"



these both look interesting, although the websites are quite amateurish and the products are pretty expensive, relatively speaking. anywhere we can find feedback on these two? are they new? i'm not opposed to taking a small risk and trying something out if it's only money to lose, but i'd like to make sure that they're not total scams before i send money away, you know ...
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AussieDavid
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   Posted 2/12/2007 10:42 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
I have tried to email Milanitin (via their website) and find out more about their product and what scientific evidence they have to back the claims they make. Every time I select 'submit' I get an internet explorer 'error' page. I also see the website has a 2006 copyright, so it seems they are new. Can't find anything good or bad about the product using google.
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StinkyJoe
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   Posted 2/12/2007 10:45 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
Redneck Rivera said...
Guys, check these out:
 
 
Something smells fishy here...
 
milanitin.com 
Domain created: 2007-01-06
Registered with godaddy.com
Registrant in Germany
Credit card processor: CCNow
Homeopathic
$95
60-day treatment plan. (One-time use?)
Money-back guarantee after 60 days
 
melatab.com 
Domain created: 2006-12-29
Registered with godaddy.com
registrant in Scotland 
Credit card processor: CCNow
Traditional Greek herbal blend.
$230 per month.
Money-back guarantee after 90 days
 
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Redneck Rivera
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   Posted 2/12/2007 10:45 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
dang, I agree...I liked their 100% guarantee though one can promise anything to get your money...
interesting, Milanitin mentions the treatment period of 60 days and "Unsatisfactory results after following instructions for 60 days automatically qualify you for a complete refund with no questions asked"....hmm...very specific if you know what I mean... anyway, here is the composition for Milanitin:


Ingredient Name Dilution
Verat alb D30+100C
Thuja D2+20C
Antim crud D10+100C
Theridion D10+100C
Ferr met D10+100C
Phosphorus D10+100C
Sulphur D10+100C

any feedback on the ingredients?
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