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Fumpa
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   Posted 8/20/2005 8:52 PM (GMT -4)   
lei.talk said...

the first time
was when durk pearson recommended dmae-h3.
within a couple of days,
my five-o'clock shadow was noticeably darker.
the second time
was when syntrax offered a new product: proxylon. 
i cut my hair every two weeks.
when I got out of the chair,
there was grey hair on the floor
and light-brown hair on my head.
a friend of mine tried the dmae-h3.
his goatee got darker,
later he decided that engaging in "cosmetic-behavior"
was "feminine" and he stopped.
 
 
/////////////////////////////////////////////////////////////
 
The following is another post provided for the purpose of my question
 
/////////////////////////////////////////////////////////////
One great though to remove grey hair would be to use the following nutrients:
 
 
    smhair   1. Pantothenic acid
        2. PABA
        3. Brewers yeast
 
Take the recommended dosage of the PABA and the pantothenic acid and take 8 of the brewers yeast. 
 
Take them all daily! Watch what happens to your roots in a couple of months.
 
Hope this works for you.
 
Let me know!
 
Dennis James
Life Extension Member
 
/////////////////////////////////////////////////////////////
 
 
My Question 
Has anyone that has been to this thread tried any of these suggested solutions, other than the original posters of course? If so then was it successful?
 
I don't mean to cast doubt upon the suggestions but would love to hear some success stories that resulted from these suggestions so I can feel confident going out and giving it a shot.
 
Thanks.
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Fumpa
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   Posted 8/20/2005 8:52 PM (GMT -4)   
leppert said...
Hasn't done a thing for mine and I've been taking it for years...
Thanks for response leppert. I didn't think that it would help with the graying but I was hoping. I recently started taking fish oil for the other benefits that it has to offer and it seems that new benefits keep getting discovered and was hoping that this would be another one of its benefits. Oh well.
 
The search continues.
 
turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn turn
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paragon
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   Posted 8/21/2005 11:31 AM (GMT -4)   
Thanks Fumpa.
I'm not familiar with dmae-h3. Is it simply a dietary supplement? As long as its not a hormone I'm game.

Is the dmae-h3 applied to the face manually?
I'm assuming the 3 part nutrient regimen is taken orally. Do you suggest doing both simultaneously?

Sorry for all the questions, don't want to jump in without knowing what I'm doing.
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Fumpa
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   Posted 8/22/2005 4:31 PM (GMT -4)   
paragon said...
Thanks Fumpa.
I'm not familiar with dmae-h3. Is it simply a dietary supplement? As long as its not a hormone I'm game.

Is the dmae-h3 applied to the face manually?
I'm assuming the 3 part nutrient regimen is taken orally. Do you suggest doing both simultaneously?

Sorry for all the questions, don't want to jump in without knowing what I'm doing.
Hi paragon. Sorry but I'm looking for the same thing you're looking for. Confirmation on the effectiveness of these suggested solutions. My cluttered messages are the cause of the confusion I'm sure.
 
I'm wanting to try these solutions and may do so soon regardless of whether or not someone confirms that these work.
 
If I do go for I'll let you and others here know when I've started and report back periodically (like when I get haircuts) on the success/failure.
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lei.talk
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   Posted 8/24/2005 7:39 AM (GMT -4)   

paragon-

Thanks Fumpa.
I'm not familiar with twinlab's dmae-h3. Is it simply a dietary supplement? As long as its not a hormone I'm game.

Is the twinlab's dmae-h3 applied to the face manually?
I'm assuming the 3 part nutrient regimen is taken orally. Do you suggest doing both simultaneously?

Sorry for all the questions, don't want to jump in without knowing what I'm doing.

all of those questions were answered earlier in the thread.

there were a lot of private messages about results, but no posts.

Post Edited (lei.talk) : 9/1/2005 9:09:12 PM (GMT-4)

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zorba990
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   Posted 8/24/2005 7:49 AM (GMT -4)   
I detailed my experiences earlier in the thread(s) on this subject.
 
Other things I am looking into (in addition to copper, zinc, dmae-h3, tyrosine, herbs, etc)
 
Melanin synthesis requires tyrosinase, which performs a step in the oxidation of DOPA (from tyrosine hydroxylation) to DOPAquinone.  Tyrosinase is a copper and histidine (amino acid) containing enzyme that the body can make which can bind oxygen forming a peroxide.
 
It seems that many (most/all?) of the things discussed here work to either increase the efficiency of copper metabolism (PABA, zinc, copper) or counteract the oxidative quality of this enzymes activity (antioxidants).  Since this enzyme uses a peroxide radical to do its work the antoxidants should protect against
oxidation of the nearby melanocytes and their dendrites (which they use to transfer the melanin to the keratinocytes).
 
One thing that has not been mentioned is histidine.  Histidine is an amino acid that is required for producing histamine.  So you might not want to take it orally unless you have a clear deficiency.  But topically, it might be able to get right where it needs to be in order to help out with tyrosinase synthesis.
 
 
However, none of the above will create a melanocyte where one does not exist.  So if all the melanocytes are gone from oxidation, and the stem cells to create new ones are also gone
then you are hosed.
 
But perhaps there is a way to stimulate the body to make more of those melanocyte specific stem cells.....(to be continued)...
 
 
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alfax
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   Posted 8/24/2005 2:10 PM (GMT -4)   
JUST 2 SPECULATIONS:

1) BOOSTING THE ENDOGENOUS ANTIOXIDANT CAPACITY OF OUR ORGANISM (taking suplements such as SODzime with Glisodin for example-which increases on average the levels of SOD/catalase by 30%) CAN delay the onset of gray hair?

2) The production of energy by the cellular mitocondria diminishes with age. The supplementation with CoQ10 can attenuate that process. One can speculate that since ALL CELULAR PROCESSES DEMAND ENERGY (including melanin sintesis) that supplementation with CoQ10 can, perhaps, delay the onset of gray hair.
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bluefin
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   Posted 8/25/2005 3:20 PM (GMT -4)   
Home Remedies and Treatment

" Amla " is the best cure for grey hair and falling hair. Regular massage of "amla" paste rubbed into the scalp has worked wonders in many cases, frequently reversing the process of greying or falling off of hair.

Massage your hairs with coconut oil and lemon everyday for at least 15 minutes. There are instances of people having black hairs even up to the age of 60-70 years by using this method.

Soak about 10 to 12 rithas and 3 to 4 shikakai pods overnight in a pint of water. Next day, boil for a few minutes and strain. Use this liquid as a normal shampoo. Separately soak 10 to 12 dried amlas in half a cup of water overnight. Strain and use as a hair conditioner after your head bath. Leave it on the hair for ten minutes and rinse your hair with clean warm water. This will leave your hair smooth and shiny and also stop premature greying of your hair.

Mix lemon juice in castor oil and beat till frothy. Add 'henna' in to it. Apply the mixture evenly over the scalp, and bathe after an hour using 'shikakai' and 'ritha' shampoo as above. This checks greying of hair.

Take a cup of strong black tea (without milk), and to this add a tablespoon of salt. When cold, strain the tea and massage it on the roots. Leave it on for an hour, and then rinse with cold water. Do not shampoo it.

Nourishment and proper grooming is very important to keep the hair texture, growth, shin and luster in a good condition. Therefore use a shampoo and conditioner that suits your hair type. Choose products that are gentle, preferably without any harsh detergent like sodium lauryl sulfate. For daily washes, use a shampoo that is mild, gentle and moisturizing. Don't use too much conditioner or else it makes hair greasy. Daily massage your hair with your fingertips; it helps proper blood circulation in the scalp.

Nourishment

Your hair needs the following nourishment:

a) Vitamin A - vitamin A is necessary for promoting a healthy scalp and gives body and glow to your hair. Include dark green vegetables and orange and yellow fruits & vegetables in your diet.

b) Vitamin B - vitamin B regulates the secretion of oil, keeps hair healthy & moisturized. Eat more of fresh green leafy vegetables, tomatoes, cauliflower, cereals, liver kidney, yogurt, bananas and green vegetables.

c) Minerals - minerals like zinc, iron and copper promote healthy hair. Food sources: zinc - red meat, chicken & green vegetables; iron - beef, dried apricots, red meat, parsley, eggs, wheat and sunflower seeds; copper - seafood, egg yolk and whole grains.

d) Proteins - consuming more of protein gives your hair natural shine and good texture. Include more of sprouted whole grains, cereals, meat and soy in your diet.
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Fumpa
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   Posted 8/27/2005 8:25 PM (GMT -4)   
zorba990 said...
I detailed my experiences earlier in the thread(s) on this subject.
 
Other things I am looking into (in addition to copper, zinc, dmae-h3, tyrosine, herbs, etc)
 
Melanin synthesis requires tyrosinase, which performs a step in the oxidation of DOPA (from tyrosine hydroxylation) to DOPAquinone.  Tyrosinase is a copper and histidine (amino acid) containing enzyme that the body can make which can bind oxygen forming a peroxide.
 
It seems that many (most/all?) of the things discussed here work to either increase the efficiency of copper metabolism (PABA, zinc, copper) or counteract the oxidative quality of this enzymes activity (antioxidants).  Since this enzyme uses a peroxide radical to do its work the antoxidants should protect against
oxidation of the nearby melanocytes and their dendrites (which they use to transfer the melanin to the keratinocytes).
 
One thing that has not been mentioned is histidine.  Histidine is an amino acid that is required for producing histamine.  So you might not want to take it orally unless you have a clear deficiency.  But topically, it might be able to get right where it needs to be in order to help out with tyrosinase synthesis.
 
 
However, none of the above will create a melanocyte where one does not exist.  So if all the melanocytes are gone from oxidation, and the stem cells to create new ones are also gone
then you are hosed.
 
But perhaps there is a way to stimulate the body to make more of those melanocyte specific stem cells.....(to be continued)...
 
 
Thanks for the informative response zorba. I'll have to go through and track down your other posts. Look forward to hearing/reading more on the "(to be continued)" topic.
Hopefully I still have the melanocytes needed to produce color. I do have a question on this.
I have a question about melanocytes. Are there certain cases where the odds are higher for the melanocyte being depleted/dead? For example, in my case I started getting my gray hairs at a very young age (18) and I'm guessing its inherited from my father's side as he also started to get his gray hairs at a young age. His progressed much quicker though and he had a full head of gray by the time he was 40 (I think).
thanks
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greyboy
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   Posted 8/28/2005 9:37 PM (GMT -4)   
United states patent: 20050058614
 
This patent describes the use of a drug used to treat glaucoma as able to reverse gray hair if applied topically. Check it out, it even tells you how to make a solution.
Let me know what you think of the information

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alfax
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   Posted 8/31/2005 1:24 PM (GMT -4)   
 
Hello Greyboy
 
I've checked the patent and it seems UNUSUALY PROMISING...
 
THE SUBSTANCE THAT SEEMS TO DO THE TRICK-BIMATOPROST-IS USED FOR TREATING GLAUCOMA, AND IS SOLD BY ALLERGAN,INC OF IRVINE,CALIFORNIA.
 
APPARENTLY THIS SUBSTANCE IS SAFE AND NON TOXIC AND IT ALSO ENHANCES HAIR GROWTH (!).
 
IT CAN BE TAKEN AS A TABLET OR APPLIED TOPICALY.
 
A 72 YEAR OLD MALE TOOK BIMATOPROST AS A TABLET 100 MG/DOSE, 3 DOSES PER DAY FOR 4 MONTHS AND A SIGNIFICANT PORTION OF HIS GRAY HAIRS HAD TURNED INTO THE ORIGINAL PIGMENT OR DARK BROWN COLOR. The authors didn't explain what they meant by "significant portion" though...
 
I WONDER IF THIS IS THE "GRAY HAIR REVERSAL PRODUCT" THAT amber mentioned here in d forum...
 
Is this the answer? WHO KNOWS ...
 
 
 
 
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greyboy
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   Posted 9/2/2005 6:09 PM (GMT -4)   

alfax,

I recieved a pm from amber and she stated that her product was being trialed in a local salon this month and she would let me know how it went, but I havent heard from her since???? she was very vague but said she had been flat out with business plans. Maybe she does have a good product, but who's to know, she's keeping it very quiet!

the interesting thing is that in the patent it basically states at the end that this information is free and to be used by anyone that knows what they are doing. From memory it suggested you apply topically for reversal of grey hair. The only thing stopping me from trying this is there was no said amount for the ingredients for topical application.

I think that we all could do some research and establish a safe formula containing this drug.

what do you think?


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alfax
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   Posted 9/2/2005 9:01 PM (GMT -4)   
information about bimatoprost:

Its chemical name is ( Z )-7-[(1 R ,2 R ,3 R ,5 S )-3, 5-Dihydroxy-2-[1 E ,3 S )-3-hydroxy-5-phenyl-1-pentenyl ]cyclopentyl]-5-N- ethylheptenamide, and its molecular weight is 415.58. Its molecular formula is C 25 H 37 NO 4

Bimatoprost is a powder, which is very soluble in ethyl alcohol and methyl alcohol and slightly soluble in water.
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alfax
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   Posted 9/2/2005 9:01 PM (GMT -4)   
greyboy

As far as i know bimatoprost is sold under medical prescription only. But (I think) anyone who knows some chemistry could made it and prepare a topical solution with it.

Unfortunately i'm not very good at practical chemistry ...
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JD Pintner
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   Posted 9/6/2005 1:44 PM (GMT -4)   
Dear Generic,
I had your problem ten years ago and the only thing that worked was "Just for Men". However after six years of itchy scalp and too frequent applications I saw a picture of myself that made me look like my mother in a wig! That scared me to my senses and I just let myself be grey. And you know what? People still like me, and some actually have more respect for me looking more my age.
Don't get me wrong, I liked looking young but I still look young for a guy with grey hair. I too have taken and still take every supplement in the book, including chlorophyll, biotin, GABA, DMAE, and many of the things "functionmed" has espoused. I currently take 53 supplements per day including everything from Udo's Choice Wholesome Fast Food to pregnenelone, to MSM, to Country Life Total Mins (Iron Free) and on and on. Let's face it, it's only hair. Trying to change it's color back through internally taken specialty compounds is an expensive, time consuming, and possibly risky proposition with a payback which is totally ego fulfilling, but won't ever make you happy. Love yourself as you are and save your supplementation for our health. You'll be just fine.
JD Pintner
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Redneck Rivera
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   Posted 9/7/2005 1:44 PM (GMT -4)   
another "miracle"?
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Redneck Rivera
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   Posted 9/7/2005 1:47 PM (GMT -4)   

no more vit E ??? shocked

http://www.cnn.com/HEALTH/men/9911/10/premature.graying.wmd/index.html

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Redneck Rivera
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   Posted 9/7/2005 1:47 PM (GMT -4)   
article: Gene Therapy for Gray Hair?
 
 
also ... one of the recorded antiaging benefits of H3, GH3 ...
return gray hair to natural color
 
i am wondering if H3, GH3 etc would work or safe to use for young people with gray hair ...
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zorba990
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   Posted 9/7/2005 9:11 PM (GMT -4)   
Statements in that article are meaningless without references.
 
IOW I don't give them any value at all personally.
 
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JD Pintner
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   Posted 9/7/2005 9:44 PM (GMT -4)   
Why does that article say "certain drugs" mentioning none specifically, but dissing vit E? And what's premature anyhow? Is 40 too young? Is 50? Should I have brown hair till I'm 90?
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zorba990
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   Posted 9/8/2005 2:51 PM (GMT -4)   
JD Pintner said...
Why does that article say "certain drugs" mentioning none specifically, but dissing vit E? And what's premature anyhow? Is 40 too young? Is 50? Should I have brown hair till I'm 90?
At this point I think gray hair is symptom of nutritional and other deficiencies brought on by aging.  I do not think aging is natural, or inevitable.
 
Those that believe there is something wrong with attempting to intervene in the aging process are certainly entitled to their opinion(s), but why they would choose to hang out here is beyond me.
 
 
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lei.talk
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   Posted 9/9/2005 11:31 PM (GMT -4)   
JD Pintner said...
Should I have brown hair till I'm 90?
you should have your natural hair color
until mal-nutrition
prevents your body from functioning properly.
 
which part of "old age"
did you think
was not caused by mal-nutrition
 
or failure to exercise your systems?
 
 
 
 
 

Post Edited (lei.talk) : 9/9/2005 11:18:52 PM (GMT-4)

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aironeous
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   Posted 9/12/2005 3:29 PM (GMT -4)   
I'm having trouble deciding how melanocytes differ in how they recieve their nutrients from other cells.
Here is a link to a picture of the cells in question that you can see that corresponds with the link that the moderator gave at the beginning of this thread that discusses the cause of melanocyte death.
I couldn't open the link that the moderator gave because I'm not a member of that journal.
No male in my family has any gray hair. None of my brothers or my dad despite being 60 or so. No female either. Yet here I have a couple showing up on the side of my head.
I have to say that it is highly coincidental with me dying my hair in the last three years. Those spots where they are showing up is where I had used a comb to comb in the dye which scratched my head. Despite the warnings on the box to not rub it in to the scalp I can remember not giving a cr*p about the warning and scratching away at the sides of my temples and using the comb to scratch also because it itched. I dyed it maybe about 5 or 6 times.
 
So now that it is a couple years later and I've actually started to study about life extension, I'm wondering about this dyeing and scratching that I did. I am also wondering - now that I know more - why aren't those follicle melanocytes any different from other cells when it comes to UV light damage, environmental toxins, and oxidation.
 
I realize they are different in that they are rapidly diving cells and so I wonder if UV light can damage a melanocyte up there to cause a p53 mutation and then we take one of these plant extracts like EGCG or sulfurophane and trigger it's shut down.
 
I would think that your head can have the highest amount of UV exposure where there are gaps in your hairs and you have shaved your head or cut it short.
Why can't we put carnosine on our heads? Supposedly this is the one thing that extends the number of times a cell divides.
 
Maybe mix it with some of the products listed in LE's skin products.
 
Can Chlorophyllin mixed with something able to penetrate into that area deliver copper to the meloncytes?
 
I'm not interested in taking too much copper which is probably easy to do. 
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aironeous
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   Posted 9/13/2005 2:49 PM (GMT -4)   
Here is a very exciting news item that I think not only applies to this discussion
 but begs the question, will LEF come out with a method to deliver this enzyme to humans?
 
"Scientists get first glimpse at how plants, most animals repair UV-damaged DNA"
 
 
This link will change as the news item gets moved to an archived file directory so read it quick.
 
 
Here is the first paragraph and a half to give you an idea of what it is about:
 
"For the first time, researchers have observed exactly how some cells are able to repair DNA damage caused by the sun's ultraviolet (UV) radiation. The Ohio State University study revealed how the enzyme photolyase uses energy from visible light to repair UV damage.
 
This enzyme is missing in all mammals, including humans, although all plants and all other animals have it.
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aironeous
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   Posted 9/15/2005 7:26 PM (GMT -4)   
Ok, well, apparently that was only exciting to me. There is a guy named Yarosh that has been working for a number of years on a way to transdermally deliver the photolyase enzyme to your skin cell along with a lot of other vitamins and enzymes
which I happen to find exciting and applicable to this thread if you include the meloncytes in the hair follicle as cells to take care of with a topical.
Here is the link to his company and the various inventions:

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