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gbalme
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  		   Posted 5/7/2009 9:38 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
Indeed it can be a better idea to do a topical application.

But I think that we have too much H2O2 in a lot of places in our body and not just under our hairs (even if it's the most apparent side with the white hairs). So it can be a good idea to bring the catalase inside the body too and not just on hairs.

Anyway I let somebody more competent than me to answer that question.
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StarGazer
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  		   Posted 5/7/2009 5:55 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
I have tried the LEF SOD with Glosidin tablets for about 3-4 mos. without any noticeable difference.  But I would like to see some others here try it as well before I rule it out. 
 
SOD has been proven to restore melanin in the hairs of mice. But in those studies, it was a SOD gel. 
 
Anyone else want to try the LEF SOD?
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Eiji
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  		   Posted 5/9/2009 10:03 PM (GMT -5)    Quote This PostAlert An Admin About This Post.

brm,

Thanks for your reply. Should I also take 1000 mg (2x 500 mg tablets) of PABA daily like you did?

If so, should one be taken at lunch and the other at dinner and are they best taken on an empty stomach?

Would it be a good idea to take Vitamin B complex with the PABA? I'm already taking 2.5mg chelated copper tablets daily but I doubt they are going to make any difference.

Also, with premature graying, would the gray reversal remain after coming off the supplements or do I need to continue taking supplements to keep the grays reversed?

brm said...

My grey is not premature. It can even be regarded as slightly belated. Quite normal in fact. I'd kept it at bay for a long time but it's taking a sharp bend now. cry

In your case, you can try paba for 6 months (not less) and the often mentionned other products: internal copper (deficiencies are often related to it), topical copper peptides, pantothenic acid, ho shou wuh. Make a choice from all this. Beware of vitamin supplements on high dosages.

Some people report interesting results with black strap molasses in cases of nutrient deficiencies. 


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brm
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  		   Posted 5/12/2009 9:29 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
Eiji,
 
Increase the dosage if you wish but start with 500 mg.  PABA is considered a vitamin B. So, you can enhance your vitamin B uptake with a vitamin B complex too or, as I do, with some brewer's yeast.
 
Hehe! Chelated copper... I've taken this one as well. Been on that stuff for 1 year or so. No result whatsoever.
 
If you were lucky enough to have some reversal with your supplements, you could try to get off them, at least partly, but I doubt that you could maintain the results. You would surely have to stay on your regimen. Anyway, golden rule: when you're on to something that work, don't drop it. I know my stuff with hairloss... I wouldn't drop my regimen or would only touch it up cautiously. 
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gbalme
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  		   Posted 5/12/2009 9:30 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
Somebody tried to take apple polyphenols ?

It seems to be a great antioxydant that also increase the level of catalase in the body, and so should reduce the peroxyde hydrogen.

I've also read on some forums that it worked for some people.

http://www.applepoly.com/catalase/
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brm
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  		   Posted 5/12/2009 3:00 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
If I remember correctly, grape seed extract contain polyphenols. I use topical grape seed extract daily (for hair loss) and have been so for two years; no result as to the greying, personally.
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Slider
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  		   Posted 5/13/2009 6:30 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
http://www.insidecosmeceuticals.com/articles/anti-aging/pueraria-mirifica---the-miracle-root-,p2.html
 
anybody heard of this before?
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brm
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  		   Posted 5/14/2009 9:31 AM (GMT -5)    Quote This PostAlert An Admin About This Post.

The product has estrogenic activity. This may be a problem since it seems it has to be taken internally.

 
Anyway, any trustworthy site to buy it from?
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StinkyJoe
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  		   Posted 5/15/2009 9:24 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
Very potent liquid catalase is used in the textile industry to breakdown H2O2 after bleaching cloth.
 
It is sold by the barrel. Any idea where to get smaller quatities, like 1 to 5 gallons?
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StinkyJoe
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  		   Posted 5/15/2009 9:24 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
If you take catalase orally, how likely is it to go to the scalp?

And what would be the dosage?
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JenJ
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  		   Posted 5/15/2009 11:34 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
Is anyone taking L-methionine....if so, any changes?

http://www.washingtontimes.com/news/2009/feb/25/bodys-own-hydrogen-peroxide-lightens-locks/
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StarGazer
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  		   Posted 5/15/2009 4:45 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Slider -

Per your post, and for others here to review, check out
http://www.puresterol.com/

Also, check out this PDF report on puresterol, which says that this herb gives you dark hair into your 80s -
http://www.puresterol.com/articles/HSI_SEPT07.pdf

I might try this if we can find a source for the product.
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brm
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  		   Posted 5/16/2009 7:14 PM (GMT -5)    Quote This PostAlert An Admin About This Post.

Yes, been taking this stuff too for two years. Plus L-cysteine.

=Nothing, my friend.

JenJ said...
Is anyone taking L-methionine....if so, any changes?

http://www.washingtontimes.com/news/2009/feb/25/bodys-own-hydrogen-peroxide-lightens-locks/

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JenJ
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  		   Posted 5/16/2009 7:14 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Stargazer,

Thanks for the link! I've been reading about this online. This may be a possible source:

http://www.ainterolherbs.com/index.php
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StarGazer
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  		   Posted 5/18/2009 9:45 AM (GMT -5)    Quote This PostAlert An Admin About This Post.

more on Puresterol:

http://www.gordonresearch.com/articles_hrt/Puresterol_Book_complete.doc

highlights:

"Puresterol® is safe . . . No evidence of toxicity has been found when rats were given 2,200 milligrams per kilogram of body weight orally, which would be the equivalent of giving woman 100 grams of Puresterol® at one time. Rats were also given 10 milligrams and 100 milligrams per kg bodyweight of P. mirifica orally every day for 90 days without evidence of any significant adverse effects. . .

 


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gbalme
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  		   Posted 5/19/2009 10:29 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
All of this stuff is s___ i think...

The only thing which appears reliable, and that i'm really waiting for is the CatSKL from EXT.

This appears to be the best solution.

Just hope it will not come out in 10 years...
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StarGazer
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  		   Posted 5/19/2009 2:48 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
CatSKYL from EXT is YEARS away.

Some of us are looking for an interim solution and trying to pass along key info to others. Sitting around and waiting for EXT's product, IF it ever even gets to the market (vast majority of compounds in the lab never do) is another option.
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grisgris
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  		   Posted 5/25/2009 8:33 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
okay, first post here. I am 42 and found my first gray hair on my 10th birthday. By the time I was in college I had quite a noticeable amount in the front around my hairline. It never really bothered me and still doesn't. So all this is to say that I was not looking for a cure for my gray hair (in fact, I kind of think it looks cool.)

But I think in my case I may have found something that is actually causing SOME of my hair to re-color. It is magnesium. I am taking quite a lot of it, about 1200 mg a day, for unrelated reasons, and after maybe two-three weeks I noticed the "fuzz" hair right at my hairline, which was mostly white, was suddenly not white any more. Since then the hair has grown in darker and darker.

I can't say if the gray strands all over my head are reverting and like anything, I wouldn't expect instant results anyway. All hair has different growth cycles so it might be that the hairline fuzz has a shorter cycle, or is in a growth cycle right now, or something like that and that is why I noticed it.

However, I have read that estimates are that over 80% of the population is magnesium deficient. Magnesium plays an important role in all kinds of physical processes and is apparently very important in the body's manufacture of DMAE. I'm not a doctor or researcher so I can't say whether this is the root reason (pun intended, sorry!) but would suspect it might be something to do with it.

I signed up for this forum so I could post to let the people who are upset about having gray hair that this may be helpful. I am taking magnesium aspartate and magnesium taurate. There are different kinds of magnesium supplements for sale and some are better absorbed than others. (Some of them will give you diarrhea if you take too much -- after all, that's why Milk of Magnesia works!) You can also use a product called magnesium oil. It's not actually an oil, but a concentrated solution of magnesium something-ate in water. Stings a bit when you put it on. According to things I've read it is a very effective way of raising your body's magnesium level quickly. Various manufacturers make it so google around if you're interested.

There's some information about magnesium in "The Ultramind Solution" (which of course talks about a lot of different nutritional issues) and online at various sites about magnesium and its purported benefits.

I hope this helps *someone*!
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gotsomegray
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  		   Posted 5/26/2009 9:17 AM (GMT -5)    Quote This PostAlert An Admin About This Post.

grisgris,

Thanks for the info.  That is awfully thoughtful of you to make that effort.  Hopefully that will work out for someone else as well.  I may try it myself sometime in the not too distant future.

To everyone else, I've tried the Joico Re:nu serum for about 7 months now with no noticeable results.  I think I'm going to call it quits on that.

I'm still very encouraged by a lot of the news coming out from the University of Bradford study and the EXT life sciences with CATSKL.  The competition between all of these different organizations will definitely speed up the pace of introducing a product for consumers.  It doesn't guarantee that a successful product will be found, but I think the competition will help.

 

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teengraygal
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  		   Posted 5/26/2009 9:26 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
Hi,

Here in India, people( atleast the doctors whom i met) are not aware of the supplements that are specific for copper deficiency. And unlike in other countries pharmacists here are not quite knowledgeable on these . So i am not able to buy copper supplements here as i dont know the name. I am desperately looking to buying copper supplements. Could someone please name a few copper supplements which are likely to be available in India so that i can go and ask for the same in a pharmacy shop?

-TeenGrayGal
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Jen
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  		   Posted 5/26/2009 6:13 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
Got the impulse to check out this thread today. I am not sure but I think like grisgris, this may be my first post. I did register some time ago. Anyway, I did some searching and had a lightbulb moment, idea I think grisgris' good results with increased magnesium may be due to the catalase-enhancing effect of magnesium, per the research which showed that one reason for graying is reduced catalase activity which leads to increased hydrogen peroxide "bleaching the hair from within."

grisgris is correct that most of the population is magnesium deficient, due to the over-consumption of processed foods that are devoid of this important mineral. Anyway, grisgris, I think your results are significant, esp. considering you've only been taking it for a few weeks!

So I did a search and I actually found a study that concluded magnesium enhances catalase actiivity!!

http://www.informaworld.com/smpp/content~content=a780332801
It can be concluded that dietary Mg supplementation could increase hepatic Mg concentration, enhance CAT mRNA expression and consequently enhance CAT activity, and the organic Mg (MgAsp or MgdiAsp) is much more efficient than the inorganic form (MgO).

I myself don't take magnesium supplements but I have a healthy diet overall (more so now that I've cut out coffee). Some months ago I discovered chia seeds, which are extremely nutritious, and like most seeds and nuts, are high in magnesium. I've been taking it every day. I've also started taking raw wheat germ for breakfast in oat milk, wiith a tblsp. or so of granular lecithin and sunflower seeds. My hair is thriving!

Although I am almost 59, my hair is still naturally brown with a few silver strands, I attribute this to a variety of factors, which can be boiled down to "diet and exercise." I can elaborate further if anyone is interested, but I think this is enough for one post. I'm excited about the magnesium/catalase connection!

hop hop
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StarGazer
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  		   Posted 5/27/2009 9:30 AM (GMT -5)    Quote This PostAlert An Admin About This Post.

There are a short article on AOL a month ago that said that sunflower seeds can stave off grey hair.  Not sure of the validity of that and it is hard to find sunflower seeds that don't have salt added to them. 

Most nuts, like Jen said are high in magnesium.  I'm not sure about sunflower seeds. 

I take Magnesium/calcium supplement every night and I sure don't notice fewer grey hairs.  Maybe it's only a certain type of magnesium supplement.


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Jen
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  		   Posted 5/27/2009 11:59 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
Yes, sunflower seeds are high in magnesium. This is a good article on their benefits:
http://www.whfoods.com/genpage.php?tname=foodspice&dbid=57
It's not hard to find the unsalted seeds. Trader Joe's has them and most natural food
stores like Whole Foods will carry them.

The study I quote from in my previous post says that the organic form of magnesium
(aspartate) is more efficient at activating the catalase enzyme.

Now I'm off to eat my brekkie of raw wheat germ/sunflower seeds/lecithin with oat milk.  A small bowl of that keeps me going all day!
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Jen
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  		   Posted 5/28/2009 3:34 PM (GMT -5)    Quote This PostAlert An Admin About This Post.
More info on foods high in magnesium:

http://www.food-info.net/uk/min/magnesium.htm

Great to see that cocoa powder appears first! I've been drinking cocoa made with organic Dagoba cocoa powder, oat milk, and agave syrup. Nice to know it may be helping to keep my brown hair!
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E. May
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  		   Posted 6/9/2009 8:43 AM (GMT -5)    Quote This PostAlert An Admin About This Post.
msdow1971 said...
I leanred a little more abotu PABA. Apparently PABA restores catalase to normal levels in some studies. Like this one http://www.ncbi.nlm.nih.gov/pubmed/11569176?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=1&log$=relatedarticles&logdbfrom=pubmed">pubmed</a>

Also apparently TMG or trimethylglycine (betaine) is better at reducing homocysteine. The relation between homocysteine and methionine (which the authors of the study previously mentioned relieves the H2O2 problem) is that homocysteine is transformed into methionine in the presence of a mthyl donor like TMG or SAMe. I'm thinking of swapping my folic acid for TMG such that I use vitamin E, selenium, TMG, NAC, and PABA. It seems to me that this should work. Like I said though I'll post my results.
I have a question about PABA.  Doesn't virtually every lotion, sunscreen and perhaps hair care product contain PABA?  If it works on gray hair and possibly restores catalase, shouldn't we have noticed something by now from the use of these products? 
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