Post Edited (Cory75) : 8/23/2006 4:05:08 PM (GMT-4)

What do u guys think of the resveratrol pills sold outside of LEF (like VITACOST ones, for example)?

Are they equally as effective as the ones sold by LEF?

i WOULD APPRECIATE VERY MUCH IF SOMEONE ANSWERS THESE QUESTIONS. 

THANKS IN ADVANCE.

What dosage?

The human equivalent dose for a 160-pound adult would be about 1575 milligrams of resveratrol to produce the health benefits noted in the mouse study. The reporters didn’t read the study carefully, published in Nature Magazine, which said a lower-dose (~364 milligrams for a 160-pound adult) produced similar benefits.

Furthermore, the mice were engorged with fat, 60% of their daily calorie intake. Americans once consumed about 45% of daily calories from fat (1965), but that number has dropped to about 34% (2002). So a lower amount of resveratrol, maybe half as much (~180 mg) would likely be effective.

Dr. Richard Hodes, director of the National Institute on Aging, which helped support the study, also said that people should wait for the results of safety testing. Substances that are safe and beneficial in small doses, like vitamins, sometimes prove to be harmful when taken in high doses, Dr. Hodes said.

One person who is not following this prudent advice, however, is Dr. Sinclair, the chief author of the study. He has long been taking resveratrol, though at a dose of only five milligrams per kilogram. Mice given that amount in a second feeding trial have shown similar, but less pronounced, results as those on the 24-milligram-a-day dose, he said. 

Results of the Turquoise Killifish study

Using 157 turquoise killifish bred by an Italian drug development company, Lay Line Genomics (which funded the study and which holds the rights for commercial exploitation of this aging model), the researchers conducted experiments on the antiaging effects of resveratrol.3 Beginning when the fish reached sexual maturity at 4 weeks of age, the researchers gave them food (bloodworm larvae—yum!) that was supplemented with resveratrol at three different concentrations: 24, 120, and 600 micrograms of resveratrol per gram of food.* (A fourth group, the controls, received no resveratrol.) The fish were given defined amounts of food twice daily so that their resveratrol intake could be accurately known.

The results were astonishing: whereas all the control fish died by 12 weeks of age (as did the fish receiving the lowest dose of resveratrol), the fish receiving the two higher doses of resveratrol lived much longer. In the fish receiving 120 mcg/g of food, the median lifespan increased by 33%, and the maximum lifespan increased by 27%. In the fish receiving 600 mcg/g of food, the median and maximum lifespans increased by 56% and 59%, respectively.

Update: Looks like from this thread

http://www.imminst.org/forum/index.php?s=&act=ST&f=6&t=14124&st=0

that 98% Resveratrol might become available. 

Update2:

Here's a source:

http://www.resveratrolforhealth.com/page/specification_resveratrol_glycon.html

Post Edited (zorba990) : 3/17/2007 4:26:27 PM (GMT-4)

Post Edited (albedo) : 5/22/2008 4:05:43 PM (GMT-4)