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The Life Extension Foundation Forums > LEF Public Forums > Dietary Supplements > New study: Creatine extends life span (in mice) and other antiaging benefits  Forum Quick Jump
 
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Will Brink
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   Posted 4/11/2007 5:04 PM (GMT -4)    Quote This PostAlert An Admin About This Post.
Hot off the presses. Very impressive findings regarding creatine! Increased life span, as well as all manner of anti aging effects such as age related neural effects and others. In particular, note the significantly lower accumulation of the lipofuscin. This is the most promising anti aging study on creatine yet I think. Hopefully the full paper is as impressive as the abstract.

Neurobiol Aging. 2007 Apr 6; [Epub ahead of print]
Creatine improves health and survival of mice.* Bender A, et al.

Department of Neurology, University of Munich, Klinikum Grosshadern, Marchioninistr. 15, Munich D-81377, Germany.

"The supplementation of creatine (Cr) has a marked neuroprotective effect in mouse models of neurodegenerative diseases . . .
 
Expression profiling showed an upregulation of genes implicated in neuronal growth, neuroprotection, and learning. These data show that Cr improves health and longevity in mice. Cr may be a promising food supplement to promote healthy human aging."
PMID: 17416441 [PubMed - as supplied by publisher]

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DapperDon
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   Posted 4/11/2007 7:21 PM (GMT -4)    Quote This PostAlert An Admin About This Post.
Do they recommend a daily dosage?

Too much creatine can cause serious kidney problems



 

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Will Brink
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   Posted 4/12/2007 7:52 PM (GMT -4)    Quote This PostAlert An Admin About This Post.
Typical human doses are 2-5g per day. There is no data at all to support your statement regarding creatine and kidney issues, and studies looking at such issues find no problems with kidneys, even at much higher doses.


- Will Brink @ www.BrinkZone.com


"A government big enough to give you everything you want, is strong enough to take everything you have." - Thomas Jefferson.

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cjb8256
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   Posted 4/16/2007 9:49 AM (GMT -4)    Quote This PostAlert An Admin About This Post.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17416441&query_hl=2&itool=pubmed_docsum
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Eating-Veggies.com
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   Posted 4/17/2007 4:17 PM (GMT -4)    Quote This PostAlert An Admin About This Post.
This is a great reason to supplement my weight training with creatine.
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