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The Life Extension Foundation Forums > LEF Public Forums > Dietary Supplements > supplementing w/ arginine and lysine  Forum Quick Jump
 
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WeMo
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I have been using 5,000 mg arginine each night before bed and nothing else I've tried gives me the energy, endurance, and clear thinking that arginine does.  In order to avoid HSV 2 outbreaks, I then supplement w/1,500 mg of lysine first thing each morning.  Would this be okay to do on a long term basis or are there potentially dangerous side effects from long term use of either arginine or lysine?
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DDye
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Anything that stimulates growth hormone release could encourage tumor growth.
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WeMo
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So, is genital herpes considered a tumor? I thought it was a virus. Does having genital herpes mean you shouldn't use arginine, even if you don't get outbreaks by supplementing w/ lysine? Thank you.
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DDye
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Genital herpes is caused by a virus, herpes simplex 1 or 2.  Having genital herpes does not necessarily mean that one shouldn't use L-arginine, if the person does not experience outbreaks in response to consuming L-arginine. 

Your third question was partially answered in my original response.

 

 

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AVACar
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I've been taking 1G of lysine per day for herpes for quite a while (due to taking some arginine) and am going to try stopping it and going with 1 rounded tsp glycine instead....not sure this is biochemically rational...but I'll try it anyway.

I rarely see the herpes issue.
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Sheryl
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My doctor is giving me LymPlus by Researched Nutritionals and it is supposed to get rid of Epstein Barr virus which I have as well as having lyme disease factors. It is also supposed to immunize you against EBV, this told me by my lyme clinic doctor who has to deal with these things all the time.

When I was on http://www.researchednutritionals.com/store/  I had a cold sore and decided to call and ask them about herpes. Turns out they have products for herpes:  If I recall properly, ImmunFactor #6 is for cold sores and ImmunFactor #7 is for genital herpes. The woman said these products would get rid of the herpes and immunize you as well.

My capsules are $83 for a month's supply and I have to take them for 18 months. Hopefully the herpes ones won't be as expensive. You need a health care professional to get them. I'll ask my doctor on my next appointment whether the herpes products are effective.

Sheryl
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WeMo
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So AVAcar, I'm confused about what I've read about supplementing w/ arginine if you have herpes.  I thought maybe it was dangerous to supplement w/ it.  But as I've done more and more research, it appears it's okay, as long as you stop if you have an outbreak.  As I said, no other supplement does as much for me (and I take 14 supplements/day) as arginine.  I don't know if it's the effects of NO or growth hormone.
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albedo
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My wife has herpes outbreaks (HSV-2?) in the buttock region (mainly during periods of intense stress) and found a clear benefit using 1000-1500 mg of L-Lysine as prophylaxis and during outbreaks. I also used L-Lysine for herpes labialis (HSV-1?) quite effectively but i am much less subject and take much care (e.g. avoiding lot of sun or exposure to long and intense heat such as saunas). I read (P. Balch) that the dose mentioned above should not be used for longer than 6 months without a break.
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AVACar
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WeMo.....I gave 500 mg arginine and 25 mg DHEA per day to my older dog...which gave him a couple more decent years. smilewinkgrin

From what I've read...you were supposed to match the arginine with an equal amount of lysine. I rarely have the herpes issue and only take 500 mg arginine.

Looks like selenium helps?

"Selenium is in the formulation because of the L-arginine, which may for some people cause activation of latent herpes. . . It's also possible to balance L-arginine with L-lysine, helping to achieve the same thing. So if folks want an extra measure of insurance against activating herpes, they can take some L-lysine, which does not interfere with the body's utilization of L-arginine for nitric oxide. . ."
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albedo
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At least for my wife, when she takes L-lysine at the very first symptoms, the amino acid is as well effective as (if not more) than valaciclovir! She is very happy with the results.

Post Edited (albedo) : 8/2/2010 5:17:39 PM (GMT-4)

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Tom.
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Excessive neovascularization can promote tumor cell metastasis. Growth hormone can up-regulate VEFG (vascular endothelial growth factor), the factor that causes new blood vessels to form.

10-Hydroxy-2-decenoic acid (10HDA) a long-chain, monounsaturated fatty acid of the steroid group, is the major fatty acid found only in Royal Jelly and has been shown to regulate VEGF.

While supplementing with something that may promote IGF-1 or growth hormone, such as arginine, it may be wise to supplement with a potent anti-tumor compound. Royal Jelly is ideal for that.

If you want, do some research on 10HDA and tumors and you'll see for yourself.

As far as arginine and herpes, I posted a study previously that demonstrated that arginine does not appear to promote herpes.

Antiviral effect of arginine against herpes simplex virus type 1

http://www.spandidos-publications.com/ijmm/23/4/495

My time is limited right now so maybe someone else can do some research to see if there is any other evidence to support that one study. Please post it here if you find any.
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