I know this thread is old, but it came up in a google search I was doing.  Just wanted to report my findings.  I tried iodine first, since I had some, and its a known antiseptic, and didn't seem as "extreme" as other solutions.  I have to say, it didn't work at all for me, but maybe I didn't give it enough time?  I did the needle scratch first (a few times actually) and did the iodine thing for 5 days, but it didn't do much except stain things dark brown.  I think any method you choose should only take a few days.

Next I tried 35% hydrogen peroxide.  I thought this was another good choice because its a great antiseptic, and considering you can treat one mole using less than 12 DROPS of the stuff, one liter will treat about 1600 moles!  :)

I found some online for $10 ($18 with shipping).  First a word of caution, 35% H2O2 is no joke, its a hazardous material, you need to be careful with it, and immediately wash any unintended skin it gets on with lots and lots water.  You can't be an idiot when handling this stuff.

I poured a little into a small container, so I would not contaminate the rest, which I put into my freezer for max storage life (it does not freeze, and will stay potent for decades if not centuries, in a freezer).

SO I scratched the mole with a pin, then I took a q-tip and dipped it into the H2O2, just a drop or probably less than a drop, it should not be dripping, if it is, shake off the excess.  Then I just dabbed the entire mole with the q-tip - it should bubble and turn white, but it didn't sting at all for me (there shouldn't be nerve endings in a mole, but maybe there could be?).  You can protect the surrounding skill by putting some petroleum jelly around the mole before you do the hydrogen peroxide application.  Another idea I had but didn't try was that you could cut a hole the exact size of your mole, in a piece of tape (obviously has to be a kind of tape that sticks well to skin, you might even use a band-aid) and put this over the mole so the mole sticks though your hole but the surrounding skin is covered and protected).

I did not put any bandages over this at all, it drys on its own after a few minutes.  I re-applied H2O2 2 or 3 times a day for 4 days (usually just morning and evening).  By day three the mole had collapsed (not as high as it used to be) and turned dark, just like a lot of people have described.  I think I could have stopped the H2O2 after day 3 but I did it one more day anyway.  I only put some neosporin (triple antibiotic) on it and a little tea tree oil for the next couple days.  It was basically just a scab, and I was waiting to see what would happen, well by day 7 I was tired of waiting, and the scab was lifting around the edges anyway, so I took some tweezers and pulled the scab off.  There is a small crater where the mole was, and the skin is pinkish/reddish and irritated which is what I would expect.  I can't wait to see how it heals and if the mole grows back. 

I have no idea if I should put some more H2O2 on to prevent the mole from growing back or not.  I am probably just going to wait and see what happens at this point, but overall I'm happy so far with the results.  I took pictures of it every day, I guess I'll wait until its done healing to post the full series from beginning to end (if anyone is interested).